2024 Science Breakthrough of the Year | Science Start-Ups: ActiTrexx | Falling Walls Venture

This award recognises the most promising science-based start-up that has successfully transformed science into business. On 7 November, finalists competed in a dynamic pitch competition, showcasing how their start-ups address today's most pressing challenges. The winning start-up will be announced as the Breakthrough of the Year in the Science Start-ups category.

This year, ActiTrexx has been awarded the main prize in the Science Start-ups category. The company has successfully treated its first patient with Actileucel, a pioneering cell therapy designed to prevent Graft-versus-Host Disease (GvHD) after stem cell transplantation. ActiTrexx is developing a platform of patent-protected cellular and biologic therapies that target the root causes of overshooting immune responses. This approach aims to reduce the need for immunosuppressants, offering new hope for patients.