Jake Brenner

Dr. Brenner, MD, PhD is an asst professor & physician in the University of Pennsylvania’s Dept of Medicine, where he takes care of ICU patients and runs a genetic medicine lab.  His lab developed the first safe & effective DNA-loaded lipid nanoparticles (DNA-LNPs), which they are applying to rare diseases not served by viral vectors, and to common chronic diseases. The lab received the Controlled Release Society’s Gene Therapy Scientific Achievement award in 2025.