Dr. Topalian is a physician-scientist credentialed in general surgery, with specialty training in surgical oncology and cancer immunology. After a 21-year tenure in the Surgery Branch of the National Cancer Institute, National Institutes of Health, she joined the Johns Hopkins faculty in June 2006 to lead the newly-established Melanoma Program in the Kimmel Cancer Center. She has published over 100 original research articles and reviews on cancer immunology, and is internationally recognized for this work. Dr. Topalian’s basic studies of human anti-tumor immune responses have provided a foundation for the translational development of immunotherapies for melanoma and other cancers, including cancer vaccines, adoptive T cell transfer, and immunomodulatory monoclonal antibodies. She was a member of the American Society of Clinical Oncology’s Melanoma Program Committee 2007-2008 and previously served as the MRA’s Chief Science Officer. She currently serves as a Board Member of the Society for the Immunotherapy of Cancer, as a member of the AACR Science and Regulatory Policy Taskforce, and as the Co-Chairperson for Immunology on the AACR Annual Meeting’s Scientific Program Committee.
John Hopkins Medicine
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