Erwin Böttinger is head of the Digital Health Center at the Hasso Plattner Institute (HPI) in Potsdam, Germany, and director of the newly formed Hasso Plattner Institute for Digital Health at Mount Sinai Health System in New York City, USA. He holds dual academic appointments as chaired Professor for Digital Health – Personalized Medicine at the joint Digital Engineering Faculty of the HPI and University Potsdam, and as Professor of Medicine and Systems Pharmacology and Therapeutics at the Icahn School of Medicine at Mount Sinai, New York City, USA. From November 2015 to July 2017 Erwin Böttinger was the CEO of the Berlin Institute of Health (BIH) where he played a key role in shaping its forward-looking strategy for ‘Personalized Medicine – Advanced Therapies’. From 2007 to 2015, he was the founding director of the Charles Bronfman Institute for Personalized Medicine at the Icahn School of Medicine at Mount Sinai in New York City, USA, and the principal architect of the Institute’s BioMe™ Biobank. Erwin Böttinger is a pioneer in groundbreaking implement- tations of personalized medicine and digital health in clinical practice.