Eleftheria Zeggini

Lian presented a method through which prostate cancer can be diagnosed from a drop of blood. Lian and her team are developing a blood test that predicts the probability of metastases based on a motility indicator.

Sri Harsha Paladugu is addressing the high failure rate of drugs in clinical trials by re-imagining human drug testing using more human-centric models, particularly the Multiple-Organs-on-Chip (MoC) technology. This innovative approach aims to better mimic human physiology, enhance drug safety, and expedite the drug development process, with a current focus…

The nominating institution Karlsruhe Institute of Technology on the breakthrough: Puchta is a pioneer who demonstrates that CRISPR/Cas as a site-specific nuclease can be used for restructuring complete plant chromosomes. He elucidated major mechanisms of DNA double strand break repair, and he is one of the leading scientists adopting this…

An estimated 2 billion people consume insects worldwide, and yet the appeal – and commercial availability – of this foodstock remains very limited, especially in the West. With more than 2,000 edible insect species on this planet, packed with high-quality protein, amino acids, vitamins, calcium, zinc, iron, oils, antioxidants and…

Using computational methods, Jiao Jiao Li optimises the conditions for growing stem cells. The cells respond to environmental changes and output the most effective biomolecules for treating a specific disease.

The nominating institution Einstein Center for Neurosciences Berlin on the breakthrough: Open Innovation (OI) offers a different way of doing research to address urgent global challenges. We developed an unique training strategy that empowers early-stage researchers to apply OI concepts into their projects. To embed our training into Berlin’s neuroscience…

Gloria Berinyuy Tata is addressing the need for improved screening procedures for the early detection of Streptococcus agalactiae, a leading cause of neonatal and maternal sepsis. Her proposed solution involves developing a novel molecular diagnostic tool based on the LAMP-CRISPR-Cas 12 technology, aiming to provide an accurate, affordable, and simple-to-use…

The nominating institution EPFL on the breakthrough: Safe and affordable housing and infrastructure are key to sustainable global development and rely on construction materials such as cement. Cement production is responsible for ~8% of global CO2 emission. Limestone calcined clay cement (LC3) allows up to 50% reduction of CO2 emission…

Professor Marcus Mall is chair of the Department of Pediatric Respiratory Medicine, Immunology and Critical Care Medicine at Charité-Universitätsmedizin Berlin, Germany. He is a physician-scientist and specialist in pediatric pulmonology and one of the founding directors of the German Center for Lung Research (DZL). His research focusses on cystic fibrosis,…