Clara Jiang explores whether statins (widely used lipid-lowering drugs) can be repurposed for treating depression by comparing the gene expression changes induced by statins and antidepressants in human cells.
Falling Walls
Falling Walls Science Summit 2023
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Repurposing Drugs: Breaking the Wall of Treating Depression
Clara Jiang is a postdoctoral research fellow at the Institute for Molecular Bioscience, the University of Queensland. Clara’s research focuses on using genomic and transcriptomic analysis to investigate the molecular impacts of drugs commonly prescribed for cardiovascular diseases, as well as using statistical genomic approaches to explore possible opportunities for drug repurposing. Clara graduated from the University of Queensland with a Bachelor of Advanced Science (First Class Honours) in 2017, and was awarded the University Medal. Clara was awarded her PhD at the University of Queensland in 2021, where she utilised bioinformatic approaches and molecular experiments to decipher the genetic aetiology of breast cancer, specifically the regulatory role of transposons or ‘jumping genes’ in modulating the transcriptional landscape in the cancer state. Clara is also a UQ Wellness ambassador and an advocate for promoting equity, diversity, and inclusion in academia.
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