Genes responsible for antibiotic production are often silent in laboratory setups. Creating semi-natural competitive communities will force bacteria to activate these genes and produce new antibiotics.
Falling Walls
Falling Walls Science Summit 2023
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Novel Bacteria from Antarctica: Breaking the Wall of Antibiotic Resistance
Stanislava Králová dived into the study of polar bacteria during her PhD research at the Masaryk University in Brno where she was lucky to attend an Antarctic expedition herself. Alongside her studies, she completed several internships abroad and met great mentors that have widened her research interests. These international experiences and years of studying Antarctic bacteria took her more in the direction of applied research and the study of bacterial secondary metabolites. Stanislava is currently conducting research on these metabolites as a Maria Curie Sklodowska fellow at the University of Vienna, Austria. The current goal of her research may sound simple (“Let’s find novel antimicrobial compounds”), but it’s quite clear that it’s by no means easy. However, she is aware that without new antibiotics with an effect on multidrug and extensively drug resistant bacteria, we may easily end up losing the war with superbugs. Thus, her greatest hope is, that with her research she can also contribute to the global effort of fighting multidrug resistant pathogens.
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