Several studies attempt to unravel the causes of excitatory/inhibitory imbalance in schizophrenia. The pitfall is the loose control of the exact target cells keeping an excessive level of abstraction. Enrico Patrono argues that implementing microfluidic chips called Brain-on-a-Chip, an innovative in-vitro-silico model for neural circuits allows high temporal and spatial control of molecules and cells in schizophrenia.
I am an Italian researcher in Neuroscience. I have extensive experience in neurophysiology and neurobiology of psychiatric disorders. I specialized in in vivo optogenetics, in vivo and in vitro opto-electrophysiology, immunohistochemistry, confocal microscopy, and molecular genetics approaches. I have extensive experience in multicultural teams, having spent much of my career abroad.