Kristína Macáková is addressing the delayed diagnosis issue in Rheumatoid Arthritis (RA) by focusing on the key process of citrullination, a crucial point in the production of disease-associated auto-antibodies. In this project, Macáková explores the correlation between markers of neutrophil activation and RA in genetically predisposed individuals, proposing a potential preventive strategy by blocking or cleaving neutrophil extracellular traps (NETs).
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Falling Walls Lab
Breaking the Wall of Rheumatoid Arthritis
Kristína Macáková
Kristína Macáková is a PhD student at the Institute of Molecular Biomedicine. Her undergraduate degree is in medical biology. Kristína completed her Master’s degree on describing alcohol dehydrogenase expression in Vibrio natriegenes. All three degrees are from the Comenius University in Bratislava. Kristína worked on her Bachelor’s and Master’s degrees at the Faculty of Natural Sciences and she is working at the Faculty of Medicine. She is currently primarily researching rheumatoid arthritis, as it is a prevalent disease but the etiopathogenesis is not yet known. Her research interests are extracellular DNA and neutrophils and their ability to produce neutrophils extracellular traps.