Sri Harsha Paladugu is addressing the high failure rate of drugs in clinical trials by re-imagining human drug testing using more human-centric models, particularly the Multiple-Organs-on-Chip (MoC) technology. This innovative approach aims to better mimic human physiology, enhance drug safety, and expedite the drug development process, with a current focus on understanding and combatting the complex process of cancer metastasis in breast cancer.
Falling Walls
Falling Walls Science Summit 2023
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Breaking the Wall of Human Drug Development
Sri Harsha Paladugu is a PhD student at the Centre for Nanoscience and Engineering at the Indian Institute of Science in Bangalore, India. There, she develops micro-systems to investigate disease biology. Sri Harsha and her team have developed a novel phenomenon based viscosity sensor for biological fluids inspection. They have also developed Multi-Organ-on-Chip (MoC) to understand how breast cancer spreads from one organ to another. This device paves the way for personalised medicine for cancer patients in the near future and will potentially disrupt the drug discovery pipeline.
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