Maliha Sharmin is addressing the challenge of developing a dengue vaccine that effectively targets all four antigenically distinct serotypes of the virus. Her proposed solution involves investigating the role of specific miRNAs in dengue virus replication and exploring the potential use of antisense oligonucleotides targeting these miRNAs as a promising antiviral therapy against dengue virus infections.
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Falling Walls Lab
Breaking the Wall of Dengue Infection
Maliha Sharmin
Maliha Sharmin is a microbiologist with expertise in molecular biology and virology. Her research focus involves elucidating the mechanisms governing miRNA expression and its functional significance during DENV infection. Maliha’s research primarily entails the identification and comprehensive characterisation of miRNAs that play critical roles in the intricate interplay between the host and the dengue virus during replication. Maliha’s goal is to employ antisense oligonucleotides to specifically target these miRNAs involved in dengue virus replication and explore the potential of miRNA-based therapeutic approaches for the treatment of dengue virus infections.