Carl-Henrik Heldin has been a professor in Molecular Cell Biology at Uppsala University, Sweden since 1992. Between 1986 and 2017 he was the Branch Director of the Ludwig Institute for Cancer Research in Uppsala. He is the chair of the Boards of the Nobel Foundation. His research interest is related to the mechanisms of signal transduction by growth regulatory factors, as well as their normal function and role in disease. In particular, he studies platelet-derived growth factor (PDGF), a major mitogen for connective tissue cells, and transforming growth factorb (TGFb), which inhibits the growth of most cell types. An important goal is to explore the possible clinical utility of signal transduction antagonists.
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