Frank Buchholz

Since 2010, Frank Buchholz is Professor of Medical Systems Biology and Head of Translational Research at the University Cancer Center (UCC) of TU Dresden. He is also Dean of Research at the Medical Faculty Carl Gustav Carus. Already during his PhD he did pioneering work on the implementation and improvement of sequence-specific recombinases in the field of genome engineering. Frank perfected this approach as a group leader at the Max Planck-Institute CBG Dresden and developed a designer-recombinase that can eliminate HIV from infected cells. This completely novel antiretroviral approach has been widely recognized as a breakthrough in enzyme technology, offering a promising new avenue for treating patients with HIV infections. Further developments of the technology has led to the establishment of two start-up companies.

Frank Buchholz was a Speaker at Falling Walls Sciencepreneurs 2023.